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What Is A MAOI?

Discover The Risks And Benefits
Of A Monoamine Oxidase Inhibitor



MAOI is the abbreviation for Monoamine Oxidase Inhibitor.

They are not usually the first or even the second choice in medication options due to the potential of serious side effects. They are usually used for individuals who have failed to respond to more common medications.

These medications are used primarily for depression and anxiety. However, they are not approved for individuals less than sixteen years old, and so are not commonly used for autism.

MAOIs prevent monoamine oxidase from breaking down monoamine neurotransmitters, such as serotonin, dopamine, melatonin, epinephrine, and norepinephrine. Thus, these medications increase the amount of various neurotransmitters between neurons and affect brain communication.

The most common types of this medication are listed below.

  • Nardil (phenelzine)
  • Parnate (tranylcypromine)

Tyramine is used for blood pressure regulation in your body. Also, tyramine is found in various foods and fermented products. Tyramine is usually broken down in the body by monoamine oxidase. Therefore, the use of MAOIs can cause tyramine to accumulate in the body leading to high blood pressure and possibly to stroke and heart attacks.

Since tyramine is formed when bacteria degrades protein, you should avoid fermented foods. Fresh foods are best. You should also avoid other foods that contain high amounts of tyramine. Examples of food to avoid are listed below.

  • Cheese – aged, processed
  • Meats – cured, smoked, luncheon, pickles, liver
  • Vegetables – soy beans, fava beans, sauerkraut
  • Yeast – brewer’s, extract (baker’s yeast is OK)
  • Alcohol - wine, beer

Other psychiatric medications should be used cautiously since they also elevate the amounts of monoamine neurotransmitters.

Hypertension or symptoms related to hypertension are the most common side effects. However, the list of possible side effects is extensive.

Please contact your physician or your pharmacist if you have further questions about your medication.

Learn more about discount online pharmacy solutions for your medication.

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